Ten years after its discovery, the implications of Crispr genome editing are profound and far-reaching, and we are only getting started. This tool, adapted from a bacterial immune system, allows us to cut and edit the genetic code in any living cell to make highly targeted changes and repairs. A small number of people with genetic diseases have been helped by Crispr therapies, highlighting the potential to impact the lives of those suffering from the approximately 7,000 genetic diseases with known causes. Trials are ongoing in diseases ranging from diabetes to infectious disease.